We refer you to the documents we file from time to time with the SEC which under the heading Risk Factors, identify important factors that could cause actual results to differ materially from those expressed by the Company verbally and in writing today, including, without limitation. Risks and uncertainties related to product commercial success, market competition, regulatory review and approval processes tempered glass case, conducting clinical trials, compliance with applicable regulatory requirements, the availability of data at the reference times, our dependence on collaboration partners and the level of costs associated with the commercialization, research and development business development and other activities.And with that, I will turn the call over to Mike.Thank you, Susan marble iphone case, and thanks to everyone for joining us on the call today. We had a productive fourth quarter and full year 2017 with strong operational performance across all components of our business.
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